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Source: http://news.yahoo.com/tellabs-ceo-rob-pullen-dies-colon-cancer-203545249--finance.html
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WASHINGTON (AP) ? The Justice Department says GlaxoSmithKline will pay $3 billion and plead guilty to promoting two popular drugs for unapproved uses and to failing to report important safety data about a diabetes drug to the Food and Drug Administration.
Government officials say it's the largest health care fraud settlement in U.S. history.
Prosecutors say GSK encouraged use of Paxil for children although it was not approved for anyone under 18. The company also promoted Wellbutrin for uses besides major depressive disorder, its only approved use. They say that between 2001 and 2007 GSK failed to report on two studies of the cardiovascular safety of Avandia, a diabetes drug.
Of the penalties, $1 billion covers criminal fines and forfeitures and $2 billion is for civil settlements with the federal and state governments.
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A pair of new R-rated films dominated the North American box office sending ticket sales soaring to a new record for the biggest June weekend in history. The comedy Ted and the drama Magic Mike both overperformed and connected with their target audiences while Tyler Perry's latest effort Madea's Witness Protection delivered his usual potent numbers. Overall, it was the third best weekend of 2012 as success came from a handful of original movies and not from one big franchise juggernaut opening. The marketplace is now in great shape entering what will be a gigantic July.
Family Guy fans came out in droves for creator Seth MacFarlane's directorial debut Ted which debuted at number one with an estimated $54.1M from 3,239 theaters for a sizzling $16,705 average. The raunchy buddy comedy about a man and his talking teddy bear scored the third largest opening ever for an R-rated comedy behind two major brand-based hits - The Hangover 2 ($85.9M) and Sex and the City ($56.8M). An original story not based on a well-known brand doing this level of business is incredible and reinforces the starpower of MacFarlane. Actors Mark Wahlberg and Mila Kunis also added star wattage and positive reviews helped too.
The Universal release cost $50M to produce and skewed towards men as expected. Studio research showed that males made up 56% of the crowd while 52% were 30 and older. The CinemaScore grade was a good A-. While distributors only retain a portion of the gross, and marketing costs are additional expenses, it is always good news to a studio when its opening weekend gross is higher than its film's budget. Friday saw a spectacular $20.7M bow, Saturday dipped 14% to $17.9M, and Universal is optimistically projecting a 13% slide on Sunday to $15.5M. Most other studios are estimating 20-30% declines for their films on Sunday. But with the Independence Day holiday falling on Wednesday and many young adults having extra leisure time this week, Ted should find its way to a solid showing in its first full week even though Tuesday sees the debut of the summer tentpole The Amazing Spider-Man which will start damaging competitors on Monday night when it begins its first midnight shows.
Channing Tatum scored his third hit of the year with the much-talked about male stripper movie Magic Mike which opened in second place with an estimated $39.2M from 2,930 locations for a sturdy $13,363 average. Women dominated the audience and business was incredibly front-loaded thanks to girls-night-out crowds that planned opening day outings. Friday premiered to a dazzling $19.4M which eventually accounted for half of all the weekend sales. Saturday tumbled by an alarming 41% to $11.4M while Warner Bros. expects Sunday to dip down 26% to $8.4M.
But the promise of beefcake with the likes of the red hot Tatum and co-star Matthew McConaughey was enough to spark excitement and good reviews didn't hurt either for the Steven Soderbergh-directed drama loosely based on producer/star Tatum's real-life stint as an exotic dancer. Studio data showed that 73% of the crowd was female and 57% was under 35. The CinemaScore grade was just a mediocre B. 2008's Sex and the City also saw a massive opening day rush from its audience of adult women. Its Saturday decline was 34% and its female share was 85%. If Magic Mike can hold up and keep attracting customers, it will become Tatum's third $100M+ grosser in six months. He's already seen his February romance hit The Vow reach $125M and his March buddy cop comedy 21 Jump Street make $138.3M.
Ted and Magic Mike offered a one-two punch of raunchy fun which paying audiences found irresistible as the overall box office broke the record for the biggest June weekend in history beating the last frame of June 2009 which saw the massive launch of Transformers: Revenge of the Fallen. Even more impressive was that the top three films this weekend were not sequels and the top five had no action tentpoles. The R-rated newbies proved that young adults will still come out and pay for original stories that truly excite them.
Those looking for clean family-friendly entertainment found it in the Disney/Pixar hit Brave which dropped from first to third place with an estimated $34M. The 49% decline was sizable given how the film is not a sequel and that the new releases provided virtually zero competition. It also pleased crowds on opening weekend earning an encouraging A grade from CinemaScore. Brave has grossed $131.7M in its first ten days and has performed much like Pixar's 2008 offering WALL?E which debuted in late June to $63.1M, fell 49% in its sophomore session to $32.5M for a ten-day start of $127.2M. Brave had the advantage of some 3D surcharges while the robot pic had the Independence Day holiday help it. With a big holiday week coming up, Brave may find its way to the neighborhood of $235M by the end of its domestic release.
Tyler Perry scored yet another hit film with the Lionsgate comedy Madea's Witness Protection which debuted in fourth with an estimated $26.4M from 2,161 theaters for a potent $12,193 average. The filmmaker's fourth movie with Madea in the title played to his loyal fan base which continued to come out. This was Perry's first summer release as most of his offerings went out in the spring or fall. Witness Protection's debut was in line with the $25.1M bow of the last Madea pic Big Happy Family.
Holding up well again in its fourth round was Paramount's animated sequel Madagascar 3 which collected an estimated $11.8M, off just 40%. The DreamWorks Animation hit has now taken in $180M domestically matching the gross of its 2008 predecessor. Europe's Most Wanted will surpass the $193.2M of 2005's original Madagascar next weekend and find itself going past $200M too. International markets saw an estimated $16.2M pushing the overseas haul to $244.2M for a global take of $424M.
In its second weekend, the action-horror-history mashup pic Abraham Lincoln: Vampire Hunter suffered a steep 63% tumble to an estimated $6M for $29M in ten days for Fox. Four films rounded out the top ten falling into the $4-5M range. Fox's sci-fi epic Prometheus took in an estimated $4.9M, down 50%, raising its total to $118.3M. The global haul now stands at $284.8M. Wes Anderson's indie hit Moonrise Kingdom jumped into the top ten for the first time thanks to an expansion from 395 to 854 theaters with an estimated $4.9M as well. The Focus release averaged $5,706 and has banked an impressive $18.4M to date with much more to come as its cume should double in the coming weeks.
Universal's effects-heavy fairy tale adventure Snow White and the Huntsman dropped 46% to an estimated $4.4M with $145.6M domestic to date. Disney's uplifting drama People Like Us was dead on arrival in its debut just barely making the top ten with an estimated $4.3M from 2,055 locations for a pitiful $2,095 average. With mixed reviews, the PG-13 pic starring Chris Pine and Elizabeth Banks failed to excite any demographic and should fade away quickly.
Two big July tentpoles kicked off their global releases this weekend overseas ahead of their U.S. openings. Fox's animated comedy Ice Age: Continental Drift - the fourth installment in the franchise and second in 3D - debuted to an estimated $78M from 34 markets ranking number one in all of them. In some Latin American markets like Argentina and Columbia it broke the all-time opening weekend box office record. Drift is the latest chapter in a lucrative franchise that has now broken the $2 billion mark this weekend in global box office. Though results in North America have been mostly flat over the years, overseas growth has been mammoth with international grosses soaring from $207M to $461M to a stunning $691M for the last film Dawn of the Dinosaurs which accounted for 78% of its global tally. All signs indicate that interest for the Ice Age franchise - overseas at least - remains quite high. It opens domestically on July 13.
Over in Asia and parts of Europe this weekend, Sony's reboot The Amazing Spider-Man set off fireworks of its own with a $50.2M debut from 13 territories led by Korea's $13.4M and Japan's $11.4M. The results were phenomenal with the 3D webslinger crushing the opening for Avengers in both Korea and India by more than 70%. The Andrew Garfield starrer hits U.S. screens this Tuesday one day before the 4th of July holiday. Sam Raimi's trio of Spider-Man films - all in 2D - grossed a combined $2.5 billion worldwide from 2002 to 2007.
After eight long weeks in the domestic top ten, the super hero sensation The Avengers finally dropped from the list finishing in eleventh place with $4.2M and a total of $606.3M from North America and $1.45 billion worldwide. Following in the footsteps of other recent franchises, Sony's newest alien installment Men in Black 3 will end up as the lowest-grossing pic in the series domestically, but will be the top title globally thanks to growth in international markets for action and 3D films. Will Smith's comeback vehicle stands at $169.6M from North America and will conclude with $175-180M including 3D surcharges and today's higher ticket prices. The first two MIB flicks did $250.1M in 1997 and $190.4M in 2002. But the overseas tally on MIB3 rose to $429.8M putting the global take at $599.4M with the $600M barrier ready to fall on Monday. The first Agent J pic sold more tickets but its worldwide gross from fifteen years ago was $589M.
Summer moviegoers continued to flock to new independent films as Fox Searchlight's Sundance award-winner Beasts of the Southern Wild debuted to terrific results in its platform bow in New York and Los Angeles with an estimated $169,000 from four locations for a powerful $42,309 average per theater. Cume since the Wednesday launch was $220,000. It was especially impressive given that it had no stars and was from a first-time director. The critically acclaimed drama adds more markets this week on Wednesday and Friday and then goes much wider on July 13.
Woody Allen's latest European postcard To Rome with Love fared well in its second weekend expansion grossing an estimated $750,000 from 29 playdates (up from five last week) for a $25,862 average. The Sony Classics title has banked $1.3M to date and is scheduled to widen across the country this Friday. With Moonrise Kingdom heading to $35M+ and The Best Exotic Marigold Hotel already above $40M, independent films this summer have carved out solid sales from upscale moviegoers interested in movies with more substance in a sea of mindless popcorn flicks.
The top ten films grossed an estimated $189.9M which was up 2% from last year when Transformers: Dark of the Moon opened at number one with $97.9M; and up 6% from 2010 when The Twilight Saga: Eclipse debuted on top with $64.8M. Both of those frames were helped by the 4th of July holiday.
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Source: http://www.rottentomatoes.com/m/1925471/news/1925471/
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Sony VAIO E15 has good graphics performance. It has sleek modern design. There are a lot of pros features such as Solid performance and graphics, great audio, sleek design and good multimedia. A very interesting thing is it has an Ivy Bridge power processor. To the size of the laptop, it has a 15 inch display. Once again, it has Intel Ivy Bridge processor. Yes, with features that are so interesting, this laptop has a price of $ 699.
For in terms of design, this laptop is wrapped with aluminum cover. create the look of a sporty and elegant.
VAIO E15 has a size of about 14.7 x 10 x 1-1.32 inches. For multitouch area, provided the size is around the 3.9 x 2.2-inch. Powered by a variety of great features such as 6GB of RAM, 2.5-GHz Intel Core i5-3210M Ivy Bridge processor and Intel HD Graphics 4000 GPU.
Let?s look at the specs of the Sony VAIO E15 below:
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in India, UK, Singapore, Thailand, Dubai, Europe about $699.99. You can buy or order this laptop at online retailer around you.
Sony VAIO E15 | Review Specs Price Sony VAIO E15
Source: http://feedproxy.google.com/~r/Techiehandy/~3/qeHeafQRB_s/
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DENVER?? Drought and wildfire fears are snuffing out some Fourth of July festivities this year.
From Utah to Indiana, state and local governments are calling off annual fireworks displays out of fear that a stray rocket could ignite tinder-dry brush and trigger a wildfire. They're also warning residents not to use fireworks, sparklers or Roman candles in backyards.
The worry is especially acute in the West, where crews are already battling out-of-control blazes in several states. Parts of the Midwest are affected, too, after weeks without any significant rain.
"We usually have a fireworks barge and a huge gala that attracts thousands of people," said Bill Appleby of the Grand Lake Area Chamber of Commerce, which represents the lakeside resort town about 90 miles northwest of Denver in the Rocky Mountains. The display is usually safe out on the water, but "we just can't risk an errant ember."
It's not uncommon for communities to delay or cancel fireworks shows because of drought conditions, but this year, the practice is more widespread.
Last year, about a third of the country was in drought. Now nearly three-quarters is, according to the latest U.S. Drought Monitor map, a weekly analysis of dryness across the nation. The parched conditions have been aggravated by a dry, mild winter and above-normal temperatures.
Fires have charred more than 1.8 million acres this year in the U.S., and much of Utah, Colorado, Wyoming and Montana have been under red-flag warnings for extreme fire danger.
In Colorado, where hundreds of homes have been destroyed by flames in the past month, firefighters have said they don't have the time or resources to stand watch over public events. At least nine public fireworks displays have been called off.
Montana hasn't called for an end to big displays yet, but Gov. Brian Schweitzer is urging people not to set off their own fireworks and has left the door open to canceling public shows.
Officials have also canceled displays or issued warnings restricting private fireworks in Arkansas, Illinois, Indiana, Kansas, Missouri, Utah and Wisconsin.
"Nobody wants to not have fireworks," said Chris Magnuson of Albion, Ind., a town of about 2,300 that postponed its annual July 4 fireworks show to Labor Day weekend after county officials banned outdoor burning. "It's just not safe enough."
The danger is real: Fireworks were blamed for more than 15,500 blazes and $36 million in property damage in 2010, according to the National Fire Protection Association in Quincy, Mass.
States have also clamped down on all kinds of outdoor fire hazards, including campfires, smoking and use of portable grills.
Paul Forman, who owns Independence Fireworks and Forman Blasters Pyrotechnics in Peru, Ind., said he understands the safety concerns, but his business has been devastated. Four customers called off fireworks shows this week, and he anticipated more cancellations before the holiday. He said his business had dropped from about 50 customers a day to a total of 11.
"This emergency order hit me like a two-by-four," Forman said.
Forman was going to deliver the fireworks in Bunker Hill, Ind., which had scheduled a show Saturday night following a parade, a picnic and the local Little League championships. Instead, Little League officials in the town of 900 about 60 miles north of Indianapolis canceled the show because of the fire risk.
Carol Russell had been looking forward to taking her family to the fireworks show. Her kids ? three teens and a 9-year-old ? are growing up, and she said this might be the last year they thought the display was cool.
"Tradition is a big deal for us. It's like a big bubble burst," Russell said.
Some states are grappling with just how far they can go in issuing bans. New Mexico Gov. Susana Martinez said she considers fireworks a risk that can be avoided, but state law allows cities and counties to ban only certain classifications of fireworks and where they can be used. More than half of the state's 33 counties and its largest cities have already imposed restrictions and urged residents to attend organized events instead of setting off their own.
"We should all be able to agree that preventing fires that could devastate our communities is a priority that transcends politics," said Martinez, who plans to push legislation again next year that would establish a system allowing for specially tailored temporary bans during extreme droughts.
Leaders of the fireworks industry, which brought in nearly $1 billion in sales nationally in 2011, question whether firework bans are legal. Steve Graves, executive director of the Indiana Fireworks Association, said people should be given credit for common sense.
Indiana law allows fireworks from June 29 to July 9 regardless of whether local burn bans are in place. Some communities have declared drought disaster emergencies to enact bans in an attempt to get around the law.
"Instead of talking about safety, they decided to treat Hoosiers like they're a bunch of idiots that can't think for themselves," Graves said.
At the TNT Fireworks stand just outside Helena, Mont., some customers planned to heed the calls to keep their fireworks under wraps for July Fourth, said stand co-owner Anna Richards.
"Would I rather make money or would I rather see Montana burn?" Richards said. "There's more to life than these two weeks."
Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Source: http://www.msnbc.msn.com/id/48026048/ns/weather/
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An opportunity has arisen for an experienced Head of PMO to join a brand business based in Bradford which has a significant ongoing change portfolio. The position will be wholly responsible for effective governance, control and management of all business change and systems enabled change across the group.
ESSENTIAL requirements:
? Significant experience of developing and maintaining a full group wide PMO for all types of business change.
? Strong experience of the full lifecycle in change management - strategic vision, business modelling, target operating model, portfolio planning (conception to business case/ sign off), delivery and benefits realisation.
? Knowledge of full range of industry standard best practices in portfolio management
? Corporate understanding - experience of operating at senior management level
? Excellent man management skills - a natural leader
DESIRABLE skills:
? Financial services sector - although this is NOT essential
? PRINCE2 and/ or MSP qualifications
The opportunity on offer is rare in the current economic climate and has a very competitive salary package on offer. The business in question is well known as a great place to work with strong values in honesty, empathy and diligence.
Register initial interest with a CV - PLEASE note that if the above essential requirements are not present, your application will not be considered.
Source: http://www.harveynash.com/uk/hnit/jobs/details.asp?jobid=1415310&Sourceapply=4
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