Monday, January 23, 2012

'30 Rock' star Tracy Morgan hospitalized at Sundance

Frazer Harrison / Getty Images

Actor Tracy Morgan attends a gala awards dinner at the Sundance film festival Sunday.

By msnbc.com staff and NBC News

Actor and comedian Tracy Morgan was hospitalized on Sunday night in Park City, Utah, where he was attending an awards ceremony as part of the Sundance Film Festival.

The "30 Rock" star?was taken to the Park City Medical Center, hospital spokeswoman Amy Roberts confirmed to NBC News.


Morgan, 43, was being honored at the Creative Coalition Spotlight Awards.

Entertainment news website TMZ quoted unidentified?sources as saying the actor "appeared extremely intoxicated during his award acceptance speech".

However,?TMZ later?posted a statement from?Morgan's publicist, Lewis Kay, which said: "Any reports of Tracy consuming alcohol are 100 percent?false. From a combination of exhaustion and altitude, Tracy is seeking medical attention."

("30 Rock"?is broadcast?on NBC. Msnbc.com is a joint venture of Microsoft Corp. and NBC Universal.)

NBC News?and msnbc.com staff contributed to this report.

Source: http://entertainment.msnbc.msn.com/_news/2012/01/23/10213849-30-rock-star-tracy-morgan-hospitalized-at-sundance-festival

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Friday, January 20, 2012

Chef Paula Deen hid diabetes, pushed high-fat food (AP)

NEW YORK ? Paula Deen, the Southern belle of butter and heavy cream, makes no apologies for waiting three years to disclose she has diabetes while continuing to dish up deep-fried cheesecake and other high-calorie, high-fat recipes on TV.

She said she isn't changing the comfort cooking that made her a star, though it isn't clear how much of it she'll continue to eat while she promotes health-conscious recipes along with a diabetes drug she's endorsing for a Danish company.

"I've always said, `Practice moderation, y'all.' I'll probably say that a little louder now," Deen said Tuesday after revealing her diagnosis on NBC's "Today" show. "You can have diabetes and have a piece of cake. You cannot have diabetes and eat a whole cake."

Health activists and one fellow chef called her a hypocrite for promoting an unhealthy diet along with a drug to treat its likely effects. Deen added her support of the Novo Nordisk company to a collection of lucrative endorsements that include Smithfield ham and Philadelphia Cream Cheese.

Deen, who will turn 65 on Thursday, said she kept her diagnosis private as she and her family figured out what to do, presumably about her health and a career built solidly on Southern cooking. Among her recipes: deep-fried cheesecake covered in chocolate and powdered sugar, and a quiche that calls for a pound of bacon.

"I really sat on this information for a few years because I said, `Oh, my gosh, what am I going to do about this? Is my life fixing to change? Am I no longer going to like my life?" she asked. "I had to have time to adjust and soak it all in and get up all the information that I could."

While Deen, who lives in Savannah, Ga., has cut out the sweet tea she routinely drank straight through to bedtime and taken up treadmill walking, she plans few changes on the air.

Government doctors say that being overweight (as Deen is), over 45 (as Deen is) and inactive (as Deen was) increase the risk for developing Type 2 diabetes. Growth of the disease in the U.S. has been closely tied to escalating obesity rates. Roughly 23 million Americans are believed to have the most common Type 2 diabetes; patients' bodies either do not produce enough insulin or do not use it efficiently, allowing excess sugar, or glucose, to accumulate in the blood.

Deen is the pitch person for Novo Nordisk's new online program, Diabetes in a New Light, which offers tips on food preparation, stress management and working with doctors on treatment. She has contributed diabetes-friendly recipes to the website and takes the company's drug Victoza, a once-daily noninsulin injection that had global sales of $734 million in the first nine months of 2011.

A recipe for Lady and Sons Lasagna, on her diabetes-conscious site, uses extra-lean ground beef and cans of unsalted tomato sauce and diced tomatoes, for a dish estimated at 260 calories a serving. Turn to Deen's collection of recipes on The Food Network's site and find Grandmother Paul's fried chicken, with Crisco shortening for frying, or baked French Toast casserole, with two cups of half-and-half and a half-pound of butter. No calorie counts are estimated.

The Novo Nordisk site links to promotional materials for the drug Victoza. Company spokeswoman Ambre Morley and Deen declined to disclose how much she is being paid.

Deen said she had no help or advice to offer the public when she was first diagnosed, but feels she's making a contribution now.

None of that matters much to outspoken chef Anthony Bourdain, who has never been a Deen fan. He told Eater.com of her diabetes announcement: "When your signature dish is hamburger in between a doughnut, and you've been cheerfully selling this stuff knowing all along that you've got Type 2 diabetes ... it's in bad taste if nothing else."

In Yuba, Wis., Judd Dvorak watches Deen cook on TV all the time with his wife. He thinks Bourdain has the right idea. Dvorak said it's wrong for Deen to accept money to become a paid spokeswoman for a diabetes drug after espousing a cooking style that helps lead to diabetes.

"It would be like someone who goes on TV and brags about how wonderful it is to smoke two packs of cigarettes a day and then when he or she gets lung cancer becomes a paid spokesperson for nicotine patches," Dvorak said. "I feel it is in very poor taste and if she chose to become an unpaid spokesperson for the American Diabetes Association, that would be a better way for her to make a difference and help fight this horrible disease."

Deen also smokes, but she considers her heavy-handed food only one piece of the diabetes puzzle, with genetics, lifestyle, stress, age and race. She said she would never advocate smoking and her diabetes is "well under control."

While making changes in her personal life, she doesn't think her TV shows ? there are three ? will look much different. She spends about 30 days a year taping, "so I'm not cooking and eating that way every day."

That's something the public doesn't necessarily know. The food, Deen said, isn't really to blame.

"I am who I am," she said. "I think the South gets a bad rap sometimes, saying our food is very unhealthy, but frankly I don't think that's the case. I think it's like any other food, whether it be Italian, French, Cajun. They all can be very high in calories and that's where we have to practice portion control and moderation."

Morley said the company didn't know Deen had diabetes when it approached her about promoting the new health initiative.

"We really just wanted to ask her, `Hey, Paula, do you think we could challenge you to change up some of your recipes and make them diabetes-friendly," Morley said. "And her reply was, `How did you guys know I had diabetes?'"

It was a surprise to the Food Network as well. Network officials found out only last week, said spokesman Jesse Derris.

"As part of the Food Network's family, our only concern is for Paula's health. We will continue to support her as she confronts this new challenge, taking her lead on what future episodes will offer her fans," he said.

Some health experts question the delay between the time Deen was diagnosed with diabetes and her move three years later to promote a healthier way of cooking and living.

"A more responsible approach would have been that once she was diagnosed with diabetes to really emphasize to her viewers the importance of eating a healthy diet," said Michael Jacobson, executive director of the Center for Science in the Public Interest.

____

Contributing to this report were Nicole Evatt in New York and AP Business Writer Linda A. Johnson in Trenton, N.J.

___

Online:

Paula Deen's Food Network page: _http://bit.ly/pGT9n

Paula Deen's diabetes-friendly recipes: ? http://www.diabetesinanewlight.com

Source: http://us.rd.yahoo.com/dailynews/rss/us/*http%3A//news.yahoo.com/s/ap/20120118/ap_on_he_me/us_paula_deen_diabetes

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Tuesday, January 17, 2012

Afghan official: 3 killed in helicopter crash (AP)

KABUL, Afghanistan ? An Afghan official says a civilian helicopter has crashed in southern Afghanistan, killing all three people on board.

Marjan Haqmal, police chief of Nad Ali district in Helmand province, says the Russian-made aircraft probably went down because of a technical malfunction.

NATO confirmed that a civilian helicopter crashed in southern Afghanistan on Monday. It said the site of the crash has been secured and that coalition forces are trying to gather more information about what happened.

NATO did not provide information about casualties.

Dozens of Russian-built cargo helicopters are used by contractors working for the NATO-led coalition.

The coalition relies heavily on helicopters to avoid using roads that are frequently mined by the insurgents.

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/ap/20120116/ap_on_re_as/as_afghanistan

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WWE Raw SuperShow results for Jan. 16, 2012

ANAHEIM, Calif. ? Interim Raw General Manager John Laurinaitis unleashed a pipe bomb of his own on WWE Champion CM Punk. First he reversed the decision of the night?s main event. Then after saying he?s sick and tired of being disrespected, he admitted he?s going to try to screw Punk at Royal Rumble. At the end of his emotional tirade, the EVP then bashed WWE Legend Mick Foley in the head with a mic!

Mark Henry, Dolph Ziggler & David Otunga? def. Chris Jericho, WWE Champion CM Punk & World Heavyweight Champion Daniel Bryan

Brodus Clay def. JTG
After dancing his way to the ring, Brodus Clay took on JTG. Relying on an aresenal of hard-hitting moves, "The Funkasaurus" made quick work of JTG.

A John Cena vs. United States Champion Jack Swagger Non-title Match ended in a No Contest
Right from the start, John Cena launched a brutal assault against the newly crowned United States Champion. After relentlessly pummeling Swagger, Cena was ready to deliver a particularly vicious blow with the steel ring steps ? when The Big Red Monster Kane appeared on the arena screen to instantly command Cena?s attention. ?I think you?re getting it,? Kane growled, referencing Cena appearing to embrace hate as their Royal Rumble Match looms. (PREVIEW)

R-Truth won an Over-the-Top Rope Challenge (WATCH)
After R-Truth revealed pictures from his trip to Disneyland (WATCH), Wade Barrett quickly lost interest. Next, The Miz and Barrett attacked Truth, but Sheamus charged in to help fend them off. Before total chaos erupted, SmackDown General Manager Theodore Long emerged to announce the four would do battle in an Over the Top Rope Challenge. The first to be eliminated was Wade Barrett by all three competitors. Later, when Sheamus was poised to eliminate The Miz, Truth rushed in and flipped both Superstars over the rope to seize the win. After the bout, Sheamus dropped Miz to the arena floor with a brutal Brogue Kick.

Kelly Kelly & Alicia Fox def. The Bella Twins (WATCH)
With celebrity gossip blogger Perez Hilton acting as the special guest ring announcer, Hilton thwarted twin magic by causing a distraction, allowing Kelly Kelly to capture victory for her team. Afterward, The Bellas dropped Hilton to the canvas, who promptly hid behind Kelly Kelly & Fox to escape more twin wrath.

Jack Swagger def. Zack Ryder to win the United States Championship (WATCH | PHOTOS)
Even though he was injured at the hands of Kane on last week?s Raw SuperShow (MORE), United States Champion Zack Ryder was forced to defend his title against Jack Swagger. The match was made in the interest of ?fairness?? by the GM, who felt a ref made a bad call in Swagger?s match with Punk on last week?s Raw SuperShow (MORE). After punishing and humiliating his injured opponent with three gutwrench powerbombs, Swagger dethroned Ryder. The win was especially sweet for Swagger, who has been chasing championship glory since losing the World Heavyweight Championship in 2010. After the match, Interim Raw GM John Laurinaitis apologized after revealing Ryder was not medically cleared to compete.

The Interim Raw GM Laurinaitis changed the main event
The night's main event was changed by the GM to: Chris Jericho, WWE Champion CM Punk & World Heavyweight Champion Daniel Bryan vs. Mark Henry, Dolph Ziggler & David Otunga.

WWE Tag Team ChampionsWWE Tag Team Champions Primo & Epico def. Kofi Kingston & Evan Bourne (WATCH | PHOTOS)
In their first title defense since winning the WWE Tag Team Championships yesterday at a WWE Live Event in Oakland?s Oracle Center (WATCH), Primo & Epico downed former champions Kofi Kingston & Evan Bourne, when Epico blasted Bourne with a backstabber. After the match, Rosa helped the duo celebrate.

Interim Raw General Manager John Laurinaitis denied Mick Foley?s request to be in the Royal Rumble Match (PHOTOS)
After Mick Foley kicked off Raw SuperShow by expressing his desire to be in the 2012 Royal Rumble Match so that his two kids could see him compete, he was quickly criticized for such a lofty dream by former United States Champion Dolph Ziggler. Foley clarified that his goal was to be in the Royal Rumble Match to win it. After more harsh words for the WWE Legend, Ziggler told Foley to ?just go away.?

Next, Ziggler?s Royal Rumble opponent, WWE Champion CM Punk, came out to greet his fellow ?unconventional? Superstar, pointing out that neither hide behind a woman. The WWE Champion also called Ziggler out for having the Interim Raw GM in his back pocket for their match at Royal Rumble.

As tensions grew in the ring, Interim Raw GM Laurinaitis emerged and said although he considered Foley?s request to be in the Royal Rumble Match, his answer was ?no?! After the blunt answer, Vickie cackled in Foley?s face.

MATCHES

Source: http://www.wwe.com/shows/raw/2012-01-16/results

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Modern Day Witch Hunter idea

For some time now I have been infatuated with the idea of witch hunters (primarily the interest grew from an old character of mine from the Elder Scrolls: Oblivion and just became my own little brainchild) and I thought to myself "Self: wouldn't it be interesting to see what a group of modern day hunters would be like?" and thus this idea was brought to life.

The concept of the game would revolve around rooting out the evils that have been making themselves known in the modern world: vampires, werewolves, cults dedicated to summoning evil gods and whatnot... basically anything evil needs to be eliminated before they become a threat. Characters would not start off knowing each other and would be brought together for a common goal in eradicating the monsters that threaten to plague our world.

I would be using a lot of information from the D20 Modern books such as classes, races, etc and characters would be free to model their characters any way they feel like.

I am still debating on playstyle however, wondering if I should have character sheets of the players (written ones) and keep track of their skills and the like and make DM rolls during larger or more integrated moments of the campaign.

Please let me know if this interests anyone and what concerns you may or may not have.

Thanks in advance!

-Brony

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/7JFxDGUpe3I/viewtopic.php

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Monday, January 16, 2012

Brain glia cells increase their DNA content to preserve vital blood-brain barrier

ScienceDaily (Jan. 13, 2012) ? The blood-brain barrier is essential for maintaining the brain's stable environment -- preventing entry of harmful viruses and bacteria and isolating the brain's specific hormonal and neurotransmitter activity from that in the rest of the body.

In addition to nerve cells, the brain contains glia cells that support and protect the neurons. In the fruit fly, the blood-brain boundary is made by glia joined into an envelope sealed around the nerve cells. As the brain rapidly expands during development, the glial envelope must grow correspondingly to remain intact. However, little has been known about how the blood-brain barrier maintains its integrity as the brain it protects develops.

Now Whitehead Institute scientists report that as the developing larval fruit fly brain grows by cell division, it instructs subperineurial glia (SPG) cells that form the blood-brain barrier to enlarge by creating multiple copies of their genomes in a process known as polyploidization. The researchers report their work this month in the journal Genes and Development.

"We think that this may be the same developmental strategy that's used in other contexts, where you need an outer layer of cells to maintain a seal, yet you also need the organ to grow during development," says Whitehead Member Terry Orr-Weaver.

Like the larval fruit fly's blood-brain barrier, cell layers in the human placenta and skin may employ polyploidization to respond to the need to expand while maintaining a sound boundary between the fetus and its surroundings, and the body and the outside world, respectively.

For preserving such barriers, polyploidy is ideal, as the cells forming the boundary enlarge without undergoing full cell division, a process that would break the tight junctions between cells.

In the larval fruit fly, polyploid SPG are necessary for maintaining the blood-brain barrier. When Yingdee Unhavaithaya, a postdoctoral researcher in Orr-Weaver's lab and first author of the Genes and Development article, prevented the SPG from making additional genome copies and becoming polyploid, the blood-brain barrier shattered as the brain continued to expand and the SPG was unable to accommodate its growth.

When allowed to progress naturally, polyploidy is flexible enough to accommodate even unusual brain expansion. After Unhavaithaya enlarged the brain by inducing a brain tumor, the SPG responded by increasing their ploidy and the blood-brain barrier remained unbroken.

This experiment also indicates that somehow the expanding brain mass is telling the SPG to increase their ploidy, but only as much as necessary to maintain the tight junctions between the SPG.

"It's a glimpse of communication between tissues during organogenesis," says Unhavaithaya. "We see different tissues trying to make a properly sized organ together. And one of the ways is by receiving instruction from the growing tissue so the other tissue can scale its size to properly conform to this tissue ratio for the organism."

For Orr-Weaver, Unhavaithaya's work could lead to additional exciting research.

"It has really opened up a whole new area to look at, so we can understand the mechanistic basis by which this communication happens," says Orr-Weaver, who is also an American Cancer Society professor of biology at MIT. "Does it happen at the organ level, or does it happen locally? There's really a lot to sort out."

This work was supported the Harold and Leila Mathers Charitable Foundation and the American Cancer Society.

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Story Source:

The above story is reprinted from materials provided by Whitehead Institute for Biomedical Research. The original article was written by Nicole Giese.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Y. Unhavaithaya, T. L. Orr-Weaver. Polyploidization of glia in neural development links tissue growth to blood-brain barrier integrity. Genes & Development, 2012; 26 (1): 31 DOI: 10.1101/gad.177436.111

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/CrlJWDdS7Gk/120113211013.htm

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